Purpose: To report a patient who presented an infectious keratitis 4 years after laser in situ keratomileusis (LASIK) without any other predisposing risk factor than the LASIK procedure itself.
Case Report: We report a 32-year-old man operated by LASIK in January 2006 who presented with infectious keratitis in the OD in April 2010. Clinical examination showed a corneal abscess at 10-o'clock position in the interface and fibrin and Tyndall 4+ in the anterior chamber. Microbiological analysis identified Pseudomonas aeruginosa as the cause of infection. The patient was given ofloxacin, sulfate neomycin, polymyxin B, and prednisolone acetate to be used every 2 h. Treatment led to clinical improvement with resolution of corneal infiltrate. Keratitis with intact epithelium by Pseudomonas can occur up to 4 years after LASIK.
Conclusions: LASIK treatment is a predisposing factor for bacterial keratitis even years after surgery. This report demonstrates the importance of continued postoperative vigilance by patient and his/her clinician.
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http://dx.doi.org/10.1097/OPX.0b013e318223c0c4 | DOI Listing |
Indian J Ophthalmol
January 2025
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
Purpose: The primary objective was to evaluate the clinical response of refractory cases of fungal keratitis to topical 1% posaconazole therapy.
Methods: Prospective longitudinal non-randomized open label dual-cohort study of 70 eyes of refractory fungal keratitis, 35 were recruited as posaconazole treatment (PCZ) group for topical 1% posaconazole therapy and compared to 35 eyes on conventional antifungal therapy. Study parameters included demographic and treatment details, visual acuity, comprehensive slit-lamp biomicroscopy, clinical photography, ASOCT at recruitment and weekly (week 1, 2, 3 and 4 after treatment initiation).
Front Ophthalmol (Lausanne)
December 2024
Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
Background: Infectious keratitis (IK) is a blinding disease and an important cause of ocular morbidity. Understanding regional trends in IK are important to understand the epidemiology and clinical outcomes of this disease.
Methods: In this 10-year retrospective review, patient characteristics including sociodemographic factors, medical history, and ocular history were collected as well as the clinical course and outcomes.
Cureus
November 2024
Ophthalmology, Universiti Sains Malaysia, Kota Bharu, MYS.
Gonococcal keratoconjunctivitis (GKC) is an aggressive infection caused by , which can cause an acute, dreadful, ulcerative keratitis resulting in blindness if left untreated. We report a rare case of bilateral GKC complicated with left eye corneal perforation. A 20-year-old male presented with bilateral eye purulent discharge associated with vision loss over the left eye for two weeks prior to presentation.
View Article and Find Full Text PDFAm J Trop Med Hyg
December 2024
Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
Infectious keratitis is a significant ocular disease that, if left untreated, can lead to blindness. Fungi are among the causative agents that can result in severe symptoms. Keratitis infections are prevalent globally, with a higher incidence reported in tropical and subtropical regions.
View Article and Find Full Text PDFJ Clin Med
November 2024
Rothschild Foundation Hospital, 75019 Paris, France.
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