Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.micinf.2011.05.008 | DOI Listing |
Publication Analysis
Top Keywords
ifn-γ response
8
response signal
8
signal transduction
8
autophagy
4
autophagy facilitates
4
facilitates ifn-γ
4
transduction autophagy
4
autophagy directly
4
directly triggered
4
triggered invaded
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!