AI Article Synopsis
- This study aimed to determine the best times to collect saliva for measuring cortisol levels as a way to evaluate stress.
- Saliva samples were collected from twelve healthy adults at three different times during the day: right after waking up, in the evening, and before bed, over a span of five days.
- Results showed that cortisol levels were highest upon waking, with the least variation in readings, suggesting morning samples are the most reliable for assessing stress-related cortisol levels.*
Article Abstract
Purpose: The purpose of this study was to clarify the day-to-day variations of salivary cortisol to discuss the appropriate timing for collecting saliva in a day for stress evaluation.
Materials And Methods: Saliva samples from twelve healthy adults were collected by means of Salivette(®) (SARSTEDT Co.) three times per day, immediately after awakening (Time1), 6:00 PM (Time2) and 30 min before going to bed (Time3), on 5 nonconsecutive days. Cortisol concentration was measured using a radioimmunoassay.
Results: Salivary cortisol concentration showed the larger value at Time1 than that at Time2. The mean value of %CV for day-to-day variation showed the smallest value at Time1 (mean: 43.1%) and the largest value at Time3 (mean: 100.3%). There were significant differences in %CV value between Time1 and Time3, Time2 (mean: 64.1%) and Time3.
Conclusions: There are considerable day-to-day variations in salivary cortisol concentration measurements. From the viewpoint of day-to-day variation, collecting saliva immediately after awakening in the morning is thought to be more advantageous for evaluating cortisol concentration.
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| http://dx.doi.org/10.1016/j.jpor.2011.04.004 | DOI Listing |
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