In this issue of Molecular Cell,Choksi et al. (2011) report the identification of an NF-κB-independent ATIA (anti-TNFα-induced apoptosis)-Thioredoxin 2 axis that inhibits TNFα- and hypoxia-induced apoptosis through elimination of excessive reactive oxygen species directly.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444288 | PMC |
| http://dx.doi.org/10.1016/j.molcel.2011.05.023 | DOI Listing |
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