The two-fluid model for vehicular traffic flow explains the traffic on arterials as a mix of stopped and running vehicles. It describes the relationship between the vehicles' running speed and the fraction of running vehicles. The two parameters of the model essentially represent 'free flow' travel time and level of interaction among vehicles, and may be used to evaluate urban roadway networks and urban corridors with partially limited access. These parameters are influenced by not only the roadway characteristics but also by behavioral aspects of driver population, e.g., aggressiveness. Two-fluid models are estimated for eight arterial corridors in Orlando, FL for this study. The parameters of the two-fluid model were used to evaluate corridor level operations and the correlations of these parameters' with rates of crashes having different types/severity. Significant correlations were found between two-fluid parameters and rear-end and angle crash rates. Rate of severe crashes was also found to be significantly correlated with the model parameter signifying inter-vehicle interactions. While there is need for further analysis, the findings suggest that the two-fluid model parameters may have potential as surrogate measures for traffic safety on urban arterial streets.
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http://dx.doi.org/10.1016/j.aap.2011.01.006 | DOI Listing |
J Biol Phys
January 2025
The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
The present article focuses on the analysis of the two-phase flow of blood via a stenosed artery under the influence of a pulsatile pressure gradient. The core and plasma regions of flow are modeled using the constitutive relations of Herschel-Bulkley and the Newtonian fluids, respectively. The problem is modeled in a cylindrical coordinate system.
View Article and Find Full Text PDFACS Omega
December 2024
School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, China.
As natural resources continue to be exploited, dense medium cyclones (DMCs) are increasingly utilized for the preconcentration of low-grade ores to meet the demands for higher feed grade, increased processing capacity, and reduced energy consumption. However, determining the optimal fineness of ferrosilicon remains ambiguous for different types of ores and is often described as more of an art than a science. This paper investigates the subtle effects of ferrosilicon fineness on flow field characteristics, medium classification, and the ore separation process using a validated numerical approach, which integrates a two-fluid model, a turbulence dispersion model, and a discrete phase model.
View Article and Find Full Text PDFUltrasonics
February 2025
Department of Engineering Mechanics and Energy, Degree Programs in Systems and Information Engineering, University of Tsukuba, Tsukuba 305-8573, Japan.
Using volumetric averaged equations from a two-fluid model, this study theoretically investigates linear pressure wave propagation in a quiescent liquid with many spherical gas bubbles. The speed and attenuation of sound are evaluated using the derived linear dispersion. Mono- and poly-disperse bubbly liquids are treated.
View Article and Find Full Text PDFMol Pharm
December 2024
School of Pharmacy, Aston University, Birmingham B4 7ET, U.K.
Spray drying is one of the leading manufacturing methods for active pharmaceutical ingredients (APIs) owing to its rapid, single-step, and cost-effective nature. It also has the capacity to generate microspheres capable of controlled release of APIs including biomolecules and vaccines. However, one of the key challenges of spray-dried formulations especially with poly(lactic--glycolic acid) (PLGA)-based controlled-release injectables is burst release, where a significant fraction of the API is released prematurely within a short period of time following administration, leading to detrimental impact on the performance and quality of end products.
View Article and Find Full Text PDFJ Clin Epidemiol
December 2024
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Department of Anesthesia, St. Michael's Hospital, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Objectives: Evaluate the utility of a joint model when analysing a patient-reported endpoint as part of a randomized controlled trial (RCT) in which censoring occurs when patients die during follow-up.
Study Design And Setting: The present study comprises two parts as follows: first we reanalyzed data from a previously published RCT comparing two fluid regimens in the first 24 hours of major abdomino-pelvic surgery ('Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery [RELIEF]' trial). In this trial, patient-reported disability was measured at multiple timepoints before and after surgery.
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