[Cognitive dysfunction in patients with subclinical hypothyroidism].

Objective: Evaluate neuropsychological changes in patients with subclinical hypothyroidism (SH).

Subjects And Methods: Cross-sectional study comparing the results of the neuropsychological evaluation of 89 SH patients and 178 individuals without thyroid disease. The participants underwent the following neuropsychological assessment: Conner's Continuous Performance Test (CPT-II), Iowa Gambling Task, Stroop Test, Wisconsin Card Sorting Test (WCST), Verbal Fluency Test (semantic and phonologic categories) and Rey Auditory Verbal Learning Test.

Results: Among the neuropsychological tests, patients showed worse performance only in cognitive flexibility (WCST) and the ability to maintain sustained attention (omission errors on the CPT-II).

Conclusions: These losses can cause detriments in the daily lives of patients, constituting potential treatment indications.