Kleine-Levine syndrome in an adolescent female and response to modafinil.

Ann Indian Acad Neurol

Department of Psychiatry, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Published: January 2011

Kleine-Levine Syndrome (KLS) is a disorder characterized by a triad of periodic hypersomnia, hyperphagia, and hypersexuality. KLS, although more common in young males, it has also been seen in females. Treatment options available for its management include mood stabilisers like lithium, stimulants like amphetamines, antidepressants and other options including electroconvulsive therapy. Modafinil is one of the new stimulant medications approved for narcolepsy. Herein, we report a young female with KLS and showing favorable response to modafinil. More data is required to establish the effectiveness of modafinil in this syndrome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108080PMC
http://dx.doi.org/10.4103/0972-2327.78052DOI Listing

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