This is a case report describing a patient at Sultan Qaboos University Hospital, Oman, with recurrent local breast cancer and axillary lymph node metastasis. The cancer was detected with (99)Tc-(m) tetrofosmin scintimammography after an equivocal mammography study.
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Hell J Nucl Med
April 2014
Kayseri Training and Research Hospital Department of Nuclear Medicine, 38010 Kayseri, Turkey.
P-glycoprotein (Pgp) overexpression has been shown to be correlated with resistance to chemotherapy in patients with malignant breast tumors. The aim of our study was to investigate the role of technetium-99m-tetrofosmin (99mTc-TF) as a functional imaging agent reflecting Pgp expression in these tumors. We prospectively studied 28 patients (26 females, 2 males; mean age, 53.
View Article and Find Full Text PDFJ BUON
August 2012
National Oncology Center Hospital, Department of Nuclear Medicine, Sofia, Bulgaria.
Purpose: To evaluate post-surgical tumor-metabolic regions outside of the computed tomography (CT)-defined volume for radiation therapy (RT) planning using functional imaging of scintimammography (SMG) ± single photon emission computerized tomography (SPECT) in breast cancer (BC) patients.
Methods: 62 operated high-risk BC females, mean age 50.45 years, underwent SMG±SPECT before RT planning.
Scintimammography is sometimes referred as a complementary diagnostic method to X-rays mammography and is the optimum examination for some patients to check suspected breast tumors. A dosimetric comparison of these diagnostic examinations is important. Estimation of the absorbed dose was achieved by calculations of internal dosimetry by Medical Internal Radiation Dose (MIRD) models and by calculations from the patients' scintigraphic images data using the MIRDOSE 3 program.
View Article and Find Full Text PDFNeoplasma
February 2009
Department of Nuclear Medicine, Pusan National University School of Medicine, Republic of Korea.
The aim of the current study was to compare the diagnostic reliability of visual and quantitative indices of double phase Tc-99m MIBI scintimammography (M-SMM) and Tc-99m Tetrofosmin scintimammography (TF-SMM) for detection of breast cancer. Double phase M-SMM and TF-SMM (early; 10 minutes, delayed; hour) were performed after injection of 925 MBq of radiotracers in 75 highly suspected breast cancer patients (malignant:49, benign:26). For visual analysis, five scoring methods were used.
View Article and Find Full Text PDFClin Nucl Med
November 2008
Department of Nuclear Medicine, University of Sassari, Sassari, Italy.
Planar scintimammography (SM) acquired with a conventional gamma camera has proved a useful complementary tool to mammography (Mx) in breast cancer (BC) diagnosis, but with unsatisfactory sensitivity in small size carcinomas. In this study we assessed the role of planar SM with a high-resolution dedicated breast camera (DBC) in BC diagnosis, comparing the results with those of Mx.A consecutive series of 145 patients scheduled for biopsy for suspected BC underwent Tc-99m tetrofosmin planar SM using a newly developed DBC.
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