Altogether 82 breast cancer patients were investigated to determine a possibility of the use of parasternal lymphoscintigraphy with colloid finely divided radiopharmaceuticals 99mTc and 198Au to form individual irradiation fields; 43 patients with fibroadenomatosis were taken as controls. Variants of the localization of parasternal lymph nodes were defined, standard and "optimum" (individual) parasternal irradiation field values were compared. 54.9% of the patients were shown to be in need of correction by increasing a standard irradiation field (5 cm wide).
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Int J Biol Macromol
January 2025
College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, China. Electronic address:
Bacterial infections impede skin wound healing, and antibacterial hydrogels have garnered significant attention in the field of wound care due to their combined therapeutic effects. In this study, an intelligent, responsive AC-Gel@Cur-Au hydrogel was developed using temperature-sensitive agarose and pH-responsive chitosan as the structural framework, infused with Gel@Cur and AuNR. The AC-Gel@Cur-Au hydrogels demonstrated excellent mechanical properties, swelling capacity, tissue adhesion, and biodegradability.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, National Observations and Research Station for Wetland Ecosystems of the Yangtze Estuary, IRDR International Center of Excellence on Risk Interconnectivity and Governance on Weather, Department of Environmental Science & Engineering, Fudan University, Shanghai 200433, Peoples' Republic of China.
Hydroxyl radical (·OH) plays a crucial role in atmospheric chemistry, regulating the oxidative potential and aerosol composition. This study reveals an unprecedented source of ·OH in the atmosphere: mineral dust-bearing microdroplet aerosols. We demonstrate that Kaolin clay particles in microdroplet aerosols trigger rapid ·OH production upon solar irradiation, with rates reaching an order of at least 10 M s.
View Article and Find Full Text PDFPhys Med
January 2025
Medical Physics Dept IRCCS San Raffaele Scientific Institution Milano Italy.
Purpose: To train and validate KB prediction models by merging a large multi-institutional cohort of whole breast irradiation (WBI) plans using tangential fields.
Methods: Ten institutions (INST1-INST10, 1481 patients) developed their KB-institutional models for left/right WBI (ten models for right and eight models for left). The transferability of models among centers was assessed based on the overlap of the geometric Principal Component (PC1) of each model when applied to other institutions and/or on the presence of significantly different optimization policies.
Appl Radiat Isot
January 2025
Experimental Nuclear Physics Department, Nuclear Research Centre, Egyptian Atomic Energy Authority, Egypt; Cyclotron Facility, Egyptian Atomic Energy Authority, Egypt.
Neutron and gamma-ray shielding design for a 30Ci (1.11TBq) Am-Be irradiation facility is studied using MCNP5 Monte Carlo simulation code. The study focuses on the optimization of the shielding layers of the previously planned neutron irradiation facility.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Department of Chemoradiotherapy, Ningbo NO.2 Hospital, Ningbo, Zhejiang, 315000, China. Electronic address:
Although immunotherapy is currently one of the most promising methods for cancer treatment, its clinical application is limited due to issues such as excessive autoimmune responses and lack of specificity. Therefore, there is a need to improve immunotherapy by integrating emerging medical technologies with traditional treatments. The activation of the cGAS-STING pathway plays a crucial role in innate immunity and antiviral defense, making it highly promising for immunotherapy and attracting significant attention.
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