Comparison of classic and derivative UV spectrophotometric methods for quantification of meloxicam and mefenamic acid in pharmaceutical preparations.

The methods for quantitative determination of meloxicam and mefenamic acid in pharmaceuticals by classic spectrophotometry - zero order derivative, first and second order derivatives spectrophotometry is described, using "peak - peak" (P-P) and "peak - zero" (P-O) measurements. The calibration curves are linear within the concentration range of 4.0 - 14.0 microg/mL for meloxicam and 14.0 - 24.0 microg/mL for mefenamic acid. The procedure is simple, rapid and the results are reliable.