Objective: The perception of pitch has recently gained attention. At present, clinical audiologic tests to assess this are hardly available. This article reports on the development of a clinical test using harmonic intonation (HI) and disharmonic intonation (DI).
Study Design: Prospective collection of normative data and pilot study in hearing-impaired subjects.
Setting: Tertiary referral center.
Patients: Normative data were collected from 90 normal-hearing subjects recruited from 3 different language backgrounds. The pilot study was conducted on 18 hearing-impaired individuals who were selected into 3 pathologic groups: high-frequency hearing loss (HF), low-frequency hearing loss (LF), and cochlear implant users (CI).
Intervention(s): Normative data collection and exploratory diagnostics by means of the newly constructed HI/DI tests using intonation patterns to find the just noticeable difference (JND) for pitch discrimination in low-frequency harmonic complex sounds presented in a same-different task.
Main Outcome Measure(s): JND for pitch discrimination using HI/DI tests in the hearing population and pathologic groups.
Results: Normative data are presented in 5 parameter statistics and box-and-whisker plots showing median JNDs of 2 (HI) and 3 Hz (DI). The results on both tests are statistically abnormal in LF and CI subjects, whereas they are not significantly abnormal in the HF group.
Conclusion: The HI and DI tests allow the clinical assessment of low-frequency pitch perception. The data obtained in this study define the normal zone for both tests. Preliminary results indicate possible abnormal TFS perception in some hearing-impaired subjects.
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http://dx.doi.org/10.1097/MAO.0b013e31821f1584 | DOI Listing |
Curr Psychiatry Rep
December 2024
University of Michigan, 4250 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Purpose Of Review: This review summarizes recent studies examining average self-compassion scores in adults with symptoms of anxiety and mood disorders. We compare these findings with our own data to help establish norms for the Self-Compassion Scale (SCS) and to explore treatment implications for patients with these disorders.
Recent Findings: Several studies have demonstrated that adults with symptoms of anxiety and mood disorders have lower self-compassion scores compared to control groups, though many of these studies have established findings based on self-reported symptoms.
Biol Psychiatry
December 2024
School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China; Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, China. Electronic address:
Understanding the heterogeneity of Alzheimer's disease (AD) is crucial for advancing precision medicine specifically tailored to this disorder. Recent research has deepened our understanding of AD heterogeneity, yet translating these insights from bench to bedside via neuroimaging heterogeneity frameworks presents significant challenges. In this review, we systematically revisit prior studies and summarize the existing methodology of data-driven neuroimaging studies for AD heterogeneity.
View Article and Find Full Text PDFProbl Radiac Med Radiobiol
December 2024
State Institution «National Research Center of Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
Objective: To determine the structure of abnormalities of bone tissue and substantiate the management tactics inacute lymphoblastic leukemia (ALL) pediatric patients and in children with no oncohematological disorders, livingin radiologically contaminated territories (RCT).
Materials And Methods: Children (n = 220) living in RCT were the study participants i.e.
JMIR Form Res
December 2024
Division of Informatics, Imaging and Data Sciences, Manchester Academic Health Science Centre, The University of Manchester, Vaughan House, Portsmouth Street, Manchester, M13 9GB, United Kingdom, 44 1613067767.
Background: The potential benefits of incorporating digital technologies into health care are well documented. For example, they can improve access for patients living in remote or underresourced locations. However, despite often having the greatest health needs, people who are older or living in more socially deprived areas may be less likely to have access to these technologies and often lack the skills to use them.
View Article and Find Full Text PDFJ Int Soc Sports Nutr
December 2025
Utah State University, Kinesiology & Health Science, Logan, UT, USA.
Background: The body composition of National Collegiate Athletic Association (NCAA) athletes is well documented but no such data exist for university club sports athletes. Additionally, the majority of norms for NCAA athletes were created from individual methods requiring assumptions.
Objective: This study used a four-component (4C) model to measure the body composition of university club sports athletes.
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