The application of cold therapy is called thermotherapy Can distinguish two major forms: local and general. At the local level is widely used in the field of physical rehabilitation, rheumatology and various surgical specialties. However the evidence on issues relating to its potential benefits, physiological reason underlying its action, or application form is not sufficiently supported. Regarding the application of cold techniques, higher expectations are focused on hypothermia induced or therapeutic, for its significant neuroprotective effects after ischemia secondary to cardiac arrest. Interest in hypothermia begins in the third decade of the twentieth century the first scientific report on induced hypothermia was published in 1945 and described its application in patients with TBI. In the following decades appeared critical research on their application, but also great shadows of its benefits. The development of protocols and the great advances in the care provided in ICUs, have increased the capacity to prevent and control the side effects of the application of this therapy Based on the literature review, describing the main uses of therapeutic hypothermia, the major indications of these techniques and the evidence of its benefits and complications arising from their use.
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Langmuir
January 2025
Tianjin Key Laboratory of Refrigeration Technology, Tianjin University of Commerce, Tianjin 300134, China.
Self-cleaning applications based on bionic surface designs requires an in-depth understanding of unique and complex wetting and evaporation processes of sessile droplets on natural biosurfaces. To this end, hydrophobic bamboo and Kalanchoe blossfeldiana leaves are excellent candidates for self-cleaning applications, but various properties, such as the heat and mass transfer processes during evaporation, remain unknown. Here, the dynamics of contact angle, radius, and heat and mass transfer during evaporation of sessile droplets on bamboo and Kalanchoe blossfeldiana leaves with roughness in the range 2.
View Article and Find Full Text PDFBrief Bioinform
November 2024
Department of Computer Science, Yonsei University, Yonsei-ro 50, Seodaemun-gu, 03722, Seoul, Republic of Korea.
Identifying new compounds that interact with a target is a crucial time-limiting step in the initial phases of drug discovery. Compound-protein complex structure-based affinity prediction models can expedite this process; however, their dependence on high-quality three-dimensional (3D) complex structures limits their practical application. Prediction models that do not require 3D complex structures for binding-affinity estimation offer a theoretically attractive alternative; however, accurately predicting affinity without interaction information presents significant challenges.
View Article and Find Full Text PDFFood Sci Nutr
January 2025
Department of Food Science and Hygiene, Faculty of Veterinary Science Ilam University Ilam Iran.
In this study, the extract of leaf and flower of was obtained using an ultrasonic-assisted extraction method. The extraction yield and the content of phenolic, flavonoid, and flavonol compounds in the flower extract were higher (13.93%, 74.
View Article and Find Full Text PDFJ Orthop Case Rep
January 2025
Arthritis and Breast Care Centre, Kurukshetra, Haryana, India.
Introduction: Gouty arthritis is a common inflammatory condition caused by the deposition of uric acid crystals in the joints, leading to intense pain, swelling, and functional impairment. Thermal therapies, including hot and cold fomentation, are often used as adjunctive treatments for managing inflammation and pain in various musculoskeletal conditions. However, the efficacy of these therapies in acute gout remains underexplored.
View Article and Find Full Text PDFThe use of virtual reality (VR) in medicine is rapidly expanding, particularly in areas like pain management, surgical training, and mental health therapy. This study examines the implementation and effects of the Cold River VR application, a fully immersive tool designed to help manage pain and anxiety during dressing changes for burn trauma patients in a Czech hospital. The Cold River application immerses patients in a peaceful, interactive virtual environment, utilizing eye-tracking technology to engage them without the need for physical controllers, which could interfere with wound care.
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