Mirazid -a purified oleo-resin extract derived from myrrh- with previously proved trematocidal activity, has been recently reported to be also effective against protozoa like Trichomonas vaginalis and cryptosporidium in humans. This experimental study aimed at investigating the possible therapeutic effect of mirazid on experimental Giardia lamblia infection in albino rats, using tinidazole as a therapeutic control. Results proved the efficacy of mirazid, as indicated by a 100% reduction in parasite- load of both intestinal and fecal parasitic counts, a direct toxic effect on Giardia trophozoite as revealed by SEM and TEM in form of cell membrane erosions together with increased cytoplasmic vaculation and dissociation, and also by reversal of the observed mucosal damage associated with Giardia after complete treatment. Starting trophozoite invasion of the mucosa was also demonstrated by TEM; its mechanism and possible pathogenic effect in giardiasis were discussed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Efficacy of myrrh extract against Eimeria labbeana-like experimental infection in Columba livia domestica: in vivo study.
BMC Vet Res
December 2024
Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Background: The Protozoan pathogen Eimeria is a significant issue in poultry production. Scientists are concerned with finding alternative strategies due to the spread of resistance against the commonly employed coccidiostats. This study examined how well myrrh extract (MyE) protected domesticated pigeons from an experimental Eimeria labbeana-like infection.
View Article and Find Full Text PDFCharacterization of Myrrh Extract Effect on Polylactide and Polypropylene Melt Spun Multifilament Yarn Structure and Properties.
Materials (Basel)
November 2024
Faculty of Mechanical Engineering and Design, Kaunas University of Technology, Studentu St. 56, 51424 Kaunas, Lithuania.
Myrrh has unique medicinal properties: it is an anti-inflammatory, antifungal, and antibacterial material. The aim of this study was to assess the influence of ethanolic myrrh extract on the production and properties of modified PP and PLA melt spun yarns. In this work, multifilament yarns of polylactide (PLA) and polypropylene (PP) containing 10 wt% myrrh resin at different melt-spinning drawing ratios (DRs) were prepared.
View Article and Find Full Text PDFAntifungal activity of Myrrh gum resin against pathogenic spp.
Ann Agric Environ Med
September 2024
Department of Biology, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Article Synopsis
- - The study investigates the effectiveness of water-based extracts from two varieties of myrrh in inhibiting the growth of various pathogenic yeasts, showcasing the historical significance of medicinal plants in healing.
- - Using diffusion techniques and mass spectrometry, the extracts demonstrated antifungal activity against five yeast strains, with essential oils exhibiting the strongest effects on specific ATCC strains and revealing 12 antimicrobial components.
- - The findings indicate that myrrh extracts possess promising antifungal properties, but additional research is needed to understand their mechanisms of action and assess safety for potential clinical use.
Gas Chromatography-Mass Spectrometry Chemical Profiling of Resin Extracts and Evaluation of Larvicidal, Antioxidant, and Cytotoxic Activities.
Molecules
April 2024
Biology Department, College of Science, Jazan University, Jazan 45142, Saudi Arabia.
Plant extracts and essential oils can be alternative environmentally friendly agents to combat pathogenic microbes and malaria vectors. Myrrh is an aromatic oligum resin that is extracted from the stem of spp. It is used in medicine as an insecticide, cytotoxic, and aromatic.
View Article and Find Full Text PDFBio-nanocomposite active packaging films based on carboxymethyl cellulose, myrrh gum, TiO nanoparticles and dill essential oil for preserving fresh-fish (Cyprinus carpio) meat quality.
Int J Biol Macromol
April 2024
Coordinación de Tecnología de Alimentos de Origen Vegetal, Centro de Investigación en Alimentación y Desarrollo, A.C., Carr. Gustavo E. Astiazarán Rosas No. 46, Col. La Victoria, C.P. 83304 Hermosillo, Sonora, Mexico.
This study developed a composite film for packaging refrigerated common carp fillets using carboxymethyl cellulose (CMC) (1.5 % w/v)/Myrrh gum (MG) (0.25 % w/v) base with the addition of titanium dioxide nanoparticles (TiO NPs) (0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!