AI Article Synopsis
- SCAMPs are integral membrane proteins involved in exocytosis and have been studied mainly in animal cells, but their roles in plants are less understood.
- Recent research suggests that plant SCAMPs have similarities to mammalian SCAMPs, although they exhibit some differences in localization and function.
- The review will compare SCAMPs in both kingdoms, provide a phylogenetic analysis, and discuss expression studies of specific Arabidopsis SCAMPs to guide future functional research.
Article Abstract
Secretory carrier membrane proteins (SCAMPs) are a family of integral membrane proteins that play roles in mediating exocytosis in animal cells. However, relatively little is known about the subcellular localization, trafficking, and function of SCAMPs in plants. Several recent studies in plant cells indicate that plant SCAMPs share many similarities with their mammalian homologs although there are differences. In this review, we will first summarize and compare animal and plant SCAMPs in terms of their subcellular localization, trafficking, and possible functions. We will then present a phylogenetic analysis of plant and animal SCAMPs. Finally, we will present expression analysis on selective Arabidopsis SCAMPs in the hope of pointing to directions for functional characterization of plant SCAMPs in the future.
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| http://dx.doi.org/10.1007/s00709-011-0295-0 | DOI Listing |
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