Aviation Medicine traces its roots to high altitude physiology more than 400 years ago. Since then, great strides have been made in this medical specialty, initially catalysed by the need to reduce pilot medical attrition during the World Wars, and more recently, fuelled by the explosive growth in globalised commercial air travel. This paper traces the historical milestones in Aviation Medicine, and maps its development in Singapore since the 1960s. Advancements in military aviation platforms and technology as well as the establishment of Singapore as an international aviation hub have propelled Aviation Medicine in Singapore to the forefront of many domains. These span Aviation Physiology training, selection medical standards, performance maximisation, as well as crew and passenger protection against communicable diseases arising from air travel. The year 2011 marks the centennial milestone of the first manned flight in Singapore, paving the way for further growth of Aviation Medicine as a mature specialty in Singapore.
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