AI Article Synopsis
- The rapid advancement in hepatic surgery has led to a significant increase in the identification and surgical management of primary hepatic space-occupying lesions (PHSOLs).
- A study conducted on 31,901 patients at the Eastern Hepatobiliary Surgery Hospital from 1982 to 2009 reveals a complex spectrum of over 100 histological types of PHSOLs.
- The research introduces a new classification system organizing PHSOLs into three main types and six subtypes, aiding clinicians and pathologists in accurate diagnosis and differentiation of these lesions.
Article Abstract
Accompanying rapid developments in hepatic surgery, the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically. This has led to many changes in the surgicopathological spectrum of PHSOLs, and has contributed to a theoretical basis for modern hepatic surgery and oncological pathology. Between 1982 and 2009 at the Eastern Hepatobiliary Surgery Hospital (EHBH) in Shanghai, 31 901 patients underwent surgery and were diagnosed as having a PHSOL. In this paper, we present an analysis of the PHSOL cases at the EHBH for this time period, along with results from a systematic literature review. We describe a surgicopathological spectrum comprising more than 100 types of PHSOLs that can be stratified into three types: tumor-like, benign, and malignant. We also stratified the PHSOLs into six subtypes derived from hepatocytes; cholangiocytes; vascular, lymphoid and hemopoietic tissues; muscular, fibrous and adipose tissues; neural and neuroendocrine tissues; and miscellaneous tissues. The present study provides a new classification system that can be used as a current reference for clinicians and pathologists to make correct diagnoses and differential diagnoses among various PHSOLs.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103789 | PMC |
| http://dx.doi.org/10.3748/wjg.v17.i19.2372 | DOI Listing |
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