We present an all-fiber bidirectional passively mode-locked soliton laser with what we believe is a novel cavity configuration. Using a four-port circulator, we incorporate two different semiconductor saturable absorber mirrors (SESAMs) into the laser cavity, which enables bidirectional mode locking. The laser allows the generation of two independent countercirculating mode-locked pulse trains, each with an individual fundamental repetition rate that can be adjusted by varying the SESAM pigtail length. Two countercirculating pulse trains with repetition rates of 21.3 and 15.2 MHz are obtained simultaneously. By controlling the intracavity loss imposed on these two pulse trains, either one of the two pulse trains can be switched on or off. The bidirectional operation with other repetition rates is also demonstrated.
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http://dx.doi.org/10.1364/OL.36.002089 | DOI Listing |
Sci Adv
January 2025
New Cornerstone Science Laboratory, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.
Deep brain stimulation technology enables the neural modulation with precise spatial control but requires permanent implantation of conduits. Here, we describe a photothermal wireless deep brain stimulation nanosystem capable of eliminating α-synuclein aggregates and restoring degenerated dopamine neurons in the substantia nigra to treat Parkinson's disease. This nanosystem (ATB NPs) consists of gold nanoshell, an antibody against the heat-sensitive transient receptor potential vanilloid family member 1 (TRPV1), and β-synuclein (β-syn) peptides with a near infrared-responsive linker.
View Article and Find Full Text PDFBrain Struct Funct
January 2025
Department of Psychiatry, Psychotherapy and Psychosomatics, School of Medicine, RWTH Aachen University, Aachen, Germany.
Physiological responses derived from audiovisual perception during assisted driving are associated with the regulation of the autonomic nervous system (ANS), especially in emergencies. However, the interaction of event-related brain activity and the ANS regulating peripheral physiological indicators (i.e.
View Article and Find Full Text PDFPacing Clin Electrophysiol
January 2025
Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: Conduction system pacing (CSP) has been reported to improve clinical outcomes in comparison of right ventricular pacing (RVP). However, the performance between CSP and RVP on the risk of new-onset atrial fibrillation (AF) remains elusive.
Methods: Four online databases were systematically searched up to July 1, 2024.
J Educ Health Promot
November 2024
Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Background: Cardiac rehabilitation programs are planned to reduce the physiological and psychological stress of Cardiovascular Disease, decrease the risk of mortality secondary to CVD, improve cardiovascular function, and help patients to achieve their highest quality of life. However, data on the safety and efficacy of exercise training (ET) in patients with implantable cardioverter defibrillators (ICDs) is sparse. Exercise interventions in those with an ICD have not been extensively studied.
View Article and Find Full Text PDFJACC Adv
January 2025
Department of Endocrinology Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Background: Early-onset ischemic heart disease (IHD) is a growing burden associated with high disability and death.
Objectives: This study aimed to estimate the burden of incidence, prevalence, and disability-adjusted life years (DALY) of early-onset IHD from 1990 to 2019.
Methods: Data on the burden of early-onset IHD (men<55 years, women<65 years), including prevalence, incidence, DALY, and deaths, were collected from the Global Burden of Disease study for 204 countries and territories from 1990 to 2019.
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