We have identified in a skin swab sample from a healthy donor a new virus that we have named human gyrovirus (HGyV) because of its similarity to the chicken anemia virus (CAV), the only previously known member of the Gyrovirus genus. In particular, this virus encodes a homolog of the CAV apoptin, a protein that selectively induces apoptosis in cancer cells. By PCR screening, HGyV was found in 5 of 115 other nonlesional skin specimens but in 0 of 92 bronchoalveolar lavages or nasopharyngeal aspirates and in 0 of 92 fecal samples.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147908 | PMC |
| http://dx.doi.org/10.1128/JVI.00639-11 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Genome analysis of gyroviruses identified in waterfowl in Arizona (USA).
Arch Virol
May 2024
The Biodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, 85287, USA.
Gyroviruses are small single-stranded DNA (ssDNA) viruses that are largely associated with birds. Chicken anemia virus is the most extensively studied gyrovirus due to its disease impact on the poultry industry. However, we know much less about gyroviruses infecting other avian species.
View Article and Find Full Text PDFMolecular analysis of variants identified from the sera of dogs and cats in China.
Vet Q
December 2024
Henan Provincial Engineering Laboratory of Insects Bio-reactor, Henan Provincial Engineering, and Technology Center of Health Products for Livestock and Poultry, Henan Provincial Engineering and Technology Center of Animal Disease Diagnosis and Integrated Control, Nanyang Normal University, Nanyang, PR China.
(GyVg1), a member of the family and genus, has been detected in chicken and human tissue samples. In this study, the DNA of GyVg1-related gyroviruses in the sera of six dogs and three cats from Central and Eastern China was identified using PCR. Alignment analysis between the nine obtained and reference GyVg1 strains revealed that the genome identity ranged from 99.
View Article and Find Full Text PDFLong read sequencing revealed proventricular virome of broiler chicken with transmission viral proventriculitis.
BMC Vet Res
June 2022
Present Address: College of Veterinary Medicine, Shandong Agricultural University, Shandong Provence, Tai'an, 271018, China.
Background: Transmissible viral proventriculitis (TVP) causes significant economic loss to the poultry industry. However, the exact causative agents are obscure. Here we examine the virome of proventriculus from specified pathogen free (SPF) chickens that reproduced by infection of proventricular homogenate from broiler chicken with TVP using long read sequencing of the Pacific Biosciences RSII platform.
View Article and Find Full Text PDFMolecular characterization of the Gyrovirus galga 1 strain detected in various zoo animals: the first report from China.
Microbes Infect
September 2022
College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China.
Since 2011, the Gyrovirus galga 1 (GyVg1, previously recognized as avian gyrovirus 2) strain has extensively been detected worldwide. The virus has been identified in several species, including chickens, humans, domestic cats, and snakes, especially in China. Therefore, in this study, the presence of GyVg1 was investigated in various zoo animals to determine whether it exists in various species in Nanyang, China.
View Article and Find Full Text PDFCross-species transmission potential of chicken anemia virus and avian gyrovirus 2.
Infect Genet Evol
April 2022
College of Animal Science and Technology, Guangxi University, Nanning 530004, China; Guangxi Centre for Animal Disease Control and Prevention, Nanning 530001, China. Electronic address:
The Gyrovirus genus consists of nonenveloped, icosahedral viruses with small circular single-stranded DNA genomes. Gyroviruses have been detected in diverse hosts, including humans, chickens, rodents, and cats. Two Gyroviruses were detected in canine serum samples using PCR in this study.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!