Here we report the synthesis and characterization of pH-responsive, self-healing hydrogels based on boronate-catechol complexation.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526106 | PMC |
http://dx.doi.org/10.1039/c1cc11928a | DOI Listing |
ACS Omega
December 2024
School of Materials Science and Engineering, Zhengzhou University, Zhengzhou, Henan 450001, P. R. China.
The development of conductive hydrogels has garnered significant attention in the field of wearable devices and smart sensors. However, the fabrication of hydrogels that possess both multifunctionality and structural stability remains a challenging task. In this study, a novel hydrogel, PHCB, was synthesized using a mild method and exhibited outstanding characteristics such as electrical conductivity, self-healing capability, antimicrobial activity, dimensional stability, and temperature sensitivity.
View Article and Find Full Text PDFJ Tissue Eng
December 2024
Center of Orthopedics, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, P.R. China.
Skeletal disorders pose significant challenges to health and quality of life, underscoring the critical need for innovative bone repair methods. Recent studies have spotlighted the promising role of extracellular vesicles (EVs) derived from bone marrow mesenchymal stem cells (BMSCs) in conjunction with biomimetic peptide (BP) WKYMVm (WK) for bone repair. This research leveraged a self-healing hydrogel as a carrier, effectively loading EVs and WK to enhance treatment efficacy.
View Article and Find Full Text PDFActa Biomater
December 2024
Institute for Vision Research, Carver College of Medicine; University of Iowa, Iowa City, IA; Department of Ophthalmology and Visual Sciences, Carver College of Medicine University of Iowa, Iowa City, IA. Electronic address:
In retinal diseases such as age-related macular degeneration (AMD) and choroideremia, a key pathophysiologic step is loss of endothelial cells of the choriocapillaris. Repopulation of choroidal vasculature early in the disease process may halt disease progression. Prior studies have shown that injection of donor cells in suspension results in significant cellular efflux and poor cell survival.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Engineering Research Centre of Chiral Hydroxyl Pharmaceutical, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007, China. Electronic address:
Hydrogels are promising wound dressings due to their extracellular matrix-like properties and tunable structure-function characteristics. Besides the physical isolation effect, hydrogel dressings are highly expected to possess tissue-adhesive performance and antibacterial capacity, which are beneficial for their clinical translations. Herein, a guar gum (GG)-based nanocomposite hydrogel was fabricated by mixing methacrylated GG (GGMA), acrylic acid, acrylated 3-aminophenylboronic acid, mangiferin (MF)-loaded cetyltrimethyl ammonium chloride (CTAC) micelles (MF@CTAC) and radical initiator.
View Article and Find Full Text PDFAdv Healthc Mater
December 2024
School of Perfume and Aroma Technology, Shanghai Institute of Technology Shanghai, Shanghai, 201418, China.
Precise and continuous monitoring of blood pressure and cardiac function is of great importance for early diagnosis and timely treatment of cardiovascular diseases. The common tests rely on on-site diagnosis and bulky equipments, hindering early diagnosis. The emerging hydrogels have gained considerable attention in skin bioelectronics by virtue of the similarities to biological tissues and versatility in mechanical, electrical, and biofunctional engineering.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!