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PTH level but not 25 (OH) vitamin D level predicts bone loss rates in the elderly.
Osteoporos Int
March 2012
Calcium Metabolism and Osteoporosis Program, American University of Beirut Medical Center, Bliss street, Beirut, Lebanon.
Unlabelled: We assessed the impact of calciotropic hormones on bone loss in 195 elderly subjects. After a median follow up of 4 years, parathyroid hormone (PTH) correlated negatively with changes in bone mineral density (BMD) at all skeletal sites. After adjustment for potential predictors of bone loss in the elderly, PTH level alone explained 3% of the variance in BMD changes at the hip.
View Article and Find Full Text PDFAge but not gender modulates the relationship between PTH and vitamin D.
Bone
August 2010
Calcium Metabolism and Osteoporosis Program, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.
Context: It is unclear whether the relationship between 25-OHD and PTH is modulated by age or gender.
Objective: To assess the 25-OHD-PTH relationship in 340 adolescents (10-17 years) and 443 elderly (65-85 years) of the same ethnic group, and living in the same sunny country.
Assessments: Calcium intake was estimated.
Expression and immunoreactivity of HCV/HBV epitopes.
World J Gastroenterol
November 2005
The Key Laboratory, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, Yunnan Province, China.
Aim: To develop the epitope-based vaccines to prevent Hepatitis C virus (HCV) / Hepatitis B virus (HBV) infections.
Methods: The HCV core epitopes C1 STNPKPQRKTKRNTNRRPQD (residuals aa2-21) and C2 VKFPGGGQIVGGVYLLPRR (residuals aa22-40), envelope epitope E GHRMAWDMMMNWSP (residuals aa315-328) and HBsAg epitope S CTTPAQGNSMFPSCCCTKPTDGNC (residuals aa124-147) were displayed in five different sites of the flock house virus capsid protein as a vector, and expressed in E. coli cells (pET-3 system).
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