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Fluorous ligand capture (FLC): a chemoselective solution-phase strategy for isolating 99mTc-labelled compounds in high effective specific activity. | LitMetric
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Fluorous ligand capture (FLC): a chemoselective solution-phase strategy for isolating 99mTc-labelled compounds in high effective specific activity.

Justin W Hicks Laura E Harrington John F Valliant

Chem Commun (Camb)

Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, Canada.

Published: July 2011

A new approach for preparing (99m)Tc-labelled compounds in high effective specific activity was developed by utilizing a novel fluorous ligand capture (FLC) agent and a chemoselective filtration strategy. This paradigm eliminates the need to use HPLC to obtain technetium(I) based molecular imaging probes free from residual precursor.

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 Source
http://dx.doi.org/10.1039/c1cc11079aDOI Listing

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