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Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study.
BMJ Open
January 2025
University of Social Welfare and Rehabilitation Science, Tehran, Iran (the Islamic Republic of).
Objective: To investigate how various morbidities affect older patients' performance on the Timed Up and Go (TUG) test.
Design: Cross-sectional study.
Setting: The seven government hospitals of Lahore, Pakistan, included are major tertiary care centres, representing an older patient population of Punjab, Pakistan.
Outcomes following intradetrusor onabotulinumtoxinA in a national cohort of nursing home residents.
BJUI Compass
January 2025
Department of Urology University of California, San Francisco San Francisco CA USA.
Objectives: To determine predictors of treatment success and complications following intradetrusor onabotulinumtoxinA injections among a large cohort of nursing home (NH) residents, representing one of the most frail and vulnerable populations in the United States.
Materials And Methods: This is a retrospective cohort study of long-stay NH residents who underwent onabotulinumtoxinA injections between 2014 and 2016. Residents were identified using the Minimum Data Set (MDS) linked to Medicare claims.
[Translated article] Toxicity of the FOLFOX-6 regimen, with or without 5-fluorouracil bolus, in metastatic colorectal cancer.
Farm Hosp
January 2025
Servicio de Oncología Médica, Hospital Universitario Juan Ramón Jiménez, Huelva, Spain.
Objective: Standard treatment of metastatic colorectal cancer includes oxaliplatin and 5-fluorouracil in continuous infusion. Although FOLFOX-6 is the reference combination, it is aggressive and has high toxicity. Variants such as the TTD regimen, which does not include folinic acid or 5-fluorouracil bolus, are used.
View Article and Find Full Text PDFAssociation of Frailty Index at 66 Years of Age with Health Care Costs and Utilization Over 10 Years in Korea: Retrospective Cohort Study.
JMIR Public Health Surveill
January 2025
Frailty Research Center, Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, United States.
Background: The long-term economic impact of frailty measured at the beginning of elderhood is unknown.
Objective: The objective of our study was to examine the association between an individual's frailty index at 66 years of age and their health care costs and utilization over 10 years.
Methods: This retrospective cohort study included 215,887 Koreans who participated in the National Screening Program for Transitional Ages at 66 years of age between 2007-2009.
A Practice Combining Exercise and Social Interaction for Community-Dwelling Elderly People and Its Outcomes.
Cureus
December 2024
Faculty of Education, University of Teacher Education Fukuoka, Fukuoka, JPN.
Introduction: The purpose of this study was to clarify the impact of an intervention combining exercise, lifestyle guidance, and community-building activities on the walking function of community-dwelling elderly individuals.
Methods: A total of 391 elderly participants (362 females, 29 males), aged 65 and above, were involved in a one-year intervention consisting of physical activities in a health exercise club, community-building activities, and dementia cafes. The walking function was assessed using an artificial intelligence (AI)-based gait analysis tool and health status was evaluated using a questionnaire.
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