AI Article Synopsis
- This study presents a new method for immobilizing oligonucleotides on AMCA slides using molecular recognition, specifically for creating 9G DNAChips.
- The method focuses on oligonucleotides that have nine consecutive guanine bases, which allows for easy and effective immobilization.
- The resulting 9G DNAChips exhibit over 90% hybridization efficiency at 25 °C within just 30 minutes.
Article Abstract
We introduce the phenomenon of molecular recognition to immobilize oligonucleotides on AMCA slides for the production of 9G DNAChips. Facile and efficient method for the immobilization of the oligonucleotides appended with consecutive nine guanine bases is described. The 9G DNAChips shows more than 90% hybridization efficiency at 25 °C in 30 min.
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| http://dx.doi.org/10.1039/c1cc12489g | DOI Listing |
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