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Initial investigation into patellofemoral morphology in hemophilic arthritis patients.
Front Surg
December 2024
Department of Orthopedics, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China.
Background: Hemophilic arthritis (HA) is associated with significant changes in the morphology of mature knee joints due to abnormal growth plate development. Previous studies have established marked distinctions between the femur and tibia of subjects with Haemophilia and those with osteoarthritis (OA). This study explored the morphological characteristics of the patella and patellofemoral joint in subjects with Haemophilia.
View Article and Find Full Text PDFMetalloproteomic Analysis of Hemophilic Arthropathy Synovial Tissue: Insights into Metal Overload and Pathogenesis.
J Thromb Haemost
December 2024
Department of Orthopaedic Surgery, The Second Hospital of Anhui Medical University, Hefei, Anhui, China. Electronic address:
Background: Hemophilic arthropathy (HA) is a joint disease characterized by local iron overload, stemming from erythrocyte rupture and closely linked to synovial lesions. However, the precise molecular characteristics of clinical HA synovial samples remain to be defined.
Objectives: To gain insight into HA synovial tissue lesions, we utilized a metalloprotein strategy to compare the metal and protein spectra of HA with those of osteoarthritis (OA) and rheumatoid arthritis (RA).
Utilizing artificial intelligence for the detection of hemarthrosis in hemophilia using point-of-care ultrasonography.
Res Pract Thromb Haemost
November 2024
Children's Hospital of Central Switzerland, Luzern, Switzerland.
Background: Recurrent hemarthrosis and resultant hemophilic arthropathy are significant causes of morbidity in persons with hemophilia, despite the marked evolution of hemophilia care. Prevention, timely diagnosis, and treatment of bleeding episodes are key. However, a physical examination or a patient's assessment of musculoskeletal pain may not accurately identify a joint bleed.
View Article and Find Full Text PDFTotal knee arthroplasty in hemophilic knees requires its own learning phase: Lessons learned from 90 cases.
Knee
December 2024
Ege University School of Medicine, Department of Orthopedics and Traumatology, Izmir, Turkey.
Background: Intraoperative challenges and complications and their course over experience in total knee arthroplasty (TKA) applications in hemophilic arthropathy have seldom been studied. Our study aimed to analyze the learning dynamics and the evolving perspective of a single arthroplasty surgeon in hemophilic knees.
Methods: The study encompassed all primary TKAs performed on hemophilic patients by a single experienced arthroplasty surgeon from May 2002 to October 2023.
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