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Complete Genome Assembly of DSM 45807 Allows the Characterization of a Novel Glycopeptide Biosynthetic Gene Cluster.
Genes (Basel)
December 2024
Department of Genetics and Biotechnology, Ivan Franko National University of Lviv, 79005 Lviv, Ukraine.
Background: Glycopeptide antibiotics (GPAs) are a very successful class of clinically relevant antibacterials, used to treat severe infections caused by Gram-positive pathogens, e.g., multidrug resistant and methicillin-resistant staphylococci.
View Article and Find Full Text PDFEffect of Antithrombin Leakage From Hemodialysis Therapy on Antithrombin Hemodynamics.
Cureus
December 2024
Clinical Laboratory Science, Graduate School of Medical Science, Kanazawa University, Kanazawa, JPN.
Introduction Hemodialysis (HD) therapy is a crucial treatment for patients with renal failure but can impact the hemodynamics of antithrombin (AT), a protein essential for regulating hemostasis and preventing thrombosis. Reduced AT activity can lead to thrombus formation at unusual sites and increase the risk of recurrent venous thromboembolism. The loss of AT during HD or hemodiafiltration (HDF) through leakage or adsorption onto dialysis membranes has not been fully investigated, and its effects on AT hemodynamics remain unclear.
View Article and Find Full Text PDFDorsal Intradural Extramedullary Bronchogenic Cysts: A Case Report and Comprehensive Literature Review.
Cureus
December 2024
Neurological Surgery, High Specialty Regional Hospital Bajio, León, MEX.
Intradural extramedullary bronchogenic cysts (IEBCs) are exceedingly rare congenital entities, composed of respiratory epithelial cells derived from the anomalous development of the embryonic foregut. Due to their exceptionally low morbidity, only limited cases are available. Consequently, the clinical features and optimal therapeutic approach remain poorly understood.
View Article and Find Full Text PDFGastroduodenal Obstruction Due to Bouveret's Syndrome: A Case Report.
Cureus
December 2024
Surgery, Hospital General Tacuba, Institute for Social Security and Services for State Workers (ISSSTE), Mexico City, MEX.
Bouveret's syndrome is a rare disorder that causes upper gastrointestinal obstruction, typically in elderly patients with a history of chronic cholelithiasis. We present an unusual case of a 58-year-old woman with untreated vesicular lithiasis who developed Bouveret's syndrome. She presented with severe abdominal pain, nausea, vomiting, and abdominal distension.
View Article and Find Full Text PDFCoping With the Crash: Intraoperative Management of Ventricular Wall Rupture During Coronary Artery Bypass Graft Surgery.
Cureus
December 2024
Anesthesiology, University of Maryland Medical Center, Baltimore, USA.
Article Synopsis
- Left ventricular (LV) free wall rupture is a serious and often deadly outcome of a heart attack, specifically after an acute myocardial infarction.
- A case is presented involving an elderly woman who experienced this rupture following anesthesia induction for a heart surgery, having suffered a heart attack just days earlier.
- The case underscores the importance of recognizing symptoms and managing severe low blood pressure during surgery, while also discussing the uncommon ways this rupture can manifest and how to effectively treat it.
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