TdaA regulates Tropodithietic acid synthesis by binding to the tdaC promoter region.

J Bacteriol

Department of Marine Biotechnology, University of Maryland Baltimore County, and Institute of Marine and Environmental Technology, Baltimore, MD 21202, USA.

Published: August 2011

Silicibacter sp. TM1040, a member of the marine Roseobacter clade, produces the antibiotic and quorum signaling molecule tropodithietic acid (TDA), encoded by tdaABCDEF. Here, we showed that an LysR-type transcriptional regulator, TdaA, is a positive regulator of tdaCDE gene expression and binds to the tdaC promoter region.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147533PMC
http://dx.doi.org/10.1128/JB.00323-11DOI Listing

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