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http://dx.doi.org/10.1093/rheumatology/ker184DOI Listing

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Article Synopsis
  • Relapsing polychondritis (RP) is a rare autoimmune disease characterized by inflammation of cartilage, affecting areas like the ear, nose, and airway.
  • Paraneoplastic RP can develop in patients after being diagnosed and treated for specific cancers.
  • In a case study, a lung adenocarcinoma patient presented with paraneoplastic RP symptoms that improved after three cycles of chemotherapy, highlighting the role of FDG PET/CT in early diagnosis and treatment planning.
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Background And Purpose: Relapsing polychondritis (RP) is a rare rheumatologic disorder that may affect the neurological system with various presentations. In this study, we present a case and summarize the clinical characteristics of RP-associated meningoencephalitis.

Case Presentation: A 48-year-old man presented with first-ever seizures that were well controlled by valproate.

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Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report.

Iran J Immunol

March 2022

Department of Rheumatology and Immunology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.

A male patient had suffered miscellaneous ocular symptoms for 20 years with auricular dysmorphosis and was diagnosed with Relapsing Polychondritis (RP) in the ear, nose, joints, and costal cartilage. The patient lost his vision owing to recurrent ocular symptoms for decades. He presented an increased IgA and was diagnosed with monoclonal gammopathy of undetermined significance (MGUS) and treated by prednisone and cyclophosphamide.

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Objective: The present article aims at describing a rare case of an RP patient who evolved with heart block and was successfully treated with corticoid pulse therapy, without the need for pacemaker insertion.

Patients And Methods: A systematic research on relapsing polychondritis (RP) and heart block (HB) published in PubMed/MEDLINE, Web of Sciences, LILACS, and Scielo from 1966 to August 2020 was performed.

Results: It was found 10 studies on RP associated with HB, and we added a case.

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