AI Article Synopsis
- Recent advancements in scientific methods have led to a surge in cell biology data, particularly focusing on the interaction between promyelocytic leukemia protein nuclear bodies (PML-NBs) and viruses.
- PML-NBs are dynamic protein aggregates in the nucleus that can be targeted by various viral components, raising interest in their potential anti-viral properties.
- A comprehensive Cytoscape network was created to visualize the interactions between PML-NBs and viruses, making it easier to navigate and identify significant case studies in this area.
Article Abstract
Due to the recent advances in instrumental and scientific methods, cell biology data are generated with increasing speed and quantity. One of these fast developing fields is the crosstalk between promyelocytic leukemia protein nuclear bodies (PML-NBs) and viruses. PML-NBs are dynamic nuclear protein aggregates which are targeted by entire viral particles, viral proteins or viral nucleic acids. Their possible anti-viral properties motivated researchers to investigate the interaction between PML-NBs and viruses in depth. Based on extensive literature data mining, we created a comprehensive PML-NB/virus crosstalk Cytoscape network, which groups not only the most common relations but also less well described findings. The network is easy to navigate and provides a biologically relevant overview which can help finding interesting case studies.
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| http://dx.doi.org/10.2741/3889 | DOI Listing |
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