AI Article Synopsis
- The study analyzes malignant parotid tumors treated at the Institut Gustave-Roussy from 1975 to 1984, highlighting the diverse histological types present.
- Management primarily relies on histology, with effective treatment involving total parotidectomy while aiming to preserve the facial nerve, followed by routine radiotherapy to reduce local recurrence.
- The 5-year survival rates for common tumor types are 49% for adenocarcinoma, 83% for adenoid cystic carcinoma, and 75% for mucoepidermoid carcinoma, with inoperable cases primarily receiving radiotherapy since chemotherapy has been ineffective.
Article Abstract
This study presents a series of malignant parotid tumours treated at the Institut Gustave-Roussy between 1975 and 1984. The lesions represented a wide variety of histological types. Few preoperative investigations were required, management being based on histology. Effective local control requires a total parotidectomy preserving the facial nerve where possible. It should be followed by routine radiotherapy which appears to reduce the incidence of local recurrence. The rate of local recurrence also depends on the histological type. It is seen more frequently in an adenocarcinoma following a pleomorphic adenoma than in simple adenocarcinoma. Patients with inoperable disease are treated with radiotherapy alone as chemotherapy has not so far been effective. Percentage 5-year survival for the three most common tumour types is as follows: adenocarcinoma: 49; adenoid cystic carcinoma: 83, and mucoepidermoid carcinoma: 75.
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| http://dx.doi.org/10.1111/j.1365-2273.1990.tb00441.x | DOI Listing |
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