The 20-deoxybryostatin 40 has been prepared using a modified Julia olefination to form the 16,17-double-bond, followed by macrolactonisation, selective deprotection and oxidation. This is the first total synthesis of a 20-deoxybryostatin.
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| http://dx.doi.org/10.1039/c1cc12332g | DOI Listing |
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