Role for proteases and HLA-G in the pathogenicity of influenza A viruses.

J Clin Virol

CNRS FRE 3011 VirPath, Virologie et Pathologie Humaine, Faculté de médecine RTH Laennec, Université Claude Bernard Lyon 1, Université de Lyon, F-69008 Lyon, France.

Published: July 2011

Influenza is one of the most common infectious diseases in humans occurring as seasonal epidemic and sporadic pandemic outbreaks. The ongoing infections of humans with avian H5N1 influenza A viruses (IAV) and the past 2009 pandemic caused by the quadruple human/avian/swine reassortant (H1N1) virus highlights the permanent threat caused by these viruses. This review aims to describe the interaction between the virus and the host, with a particular focus on the role of proteases and HLA-G in the pathogenicity of influenza viruses.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcv.2011.04.013DOI Listing

Publication Analysis

Top Keywords

influenza viruses
12
role proteases
8
proteases hla-g
8
hla-g pathogenicity
8
pathogenicity influenza
8
influenza
4
viruses
4
viruses influenza
4
influenza common
4
common infectious
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!