AI Article Synopsis
- Guar gum has a hypolipidemic effect, likely due to its ability to change lipid adsorption and intestinal viscosity.
- Rats fed a diet with 5% guar gum showed lower lymph flow and lipid transport compared to those fed a cellulose diet.
- The study highlights that higher water-holding capacity, settling volume, and viscosity of guar gum contribute to its effectiveness in reducing lipid absorption.
Article Abstract
Guar gum has a well-recognized hypolipidemic effect. This effect is thought to be due to the physicochemical properties of guar gum, which may cause changes in adsorption of lipids or the viscosity of the intestinal contents. Guar gum is a non-specific absorption inhibitor of any type of lipid-soluble compound. Permanent lymph duct cannulation was performed on rats to investigate the effects of dietary guar gum on lymph flow and lipid transport. Rats fed a 5% guar gum diet were compared with those fed a 5% cellulose diet, and lymph was collected after feeding. The water-holding capacity (WHC), settling volume in water (SV), and viscosity of guar gum were compared with those of cellulose. Rats fed with the guar gum diet had significantly lower lymph flow and lymphatic lipid transport than did rats fed with the cellulose diet. The WHC, SV, and viscosity of guar gum were significantly higher than those of cellulose. We propose that dietary guar gum reduces lymph flow and thereby diminishes lipid transport by means of its physicochemical properties related to water behavior in the intestine.
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| http://dx.doi.org/10.1007/s11745-011-3570-0 | DOI Listing |
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