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BMC Geriatr
December 2024
Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Background: The high prevalence of underweight individuals is an important issue that has become increasingly common. Therefore, this study investigated the association between body mass index (BMI) and health-related quality of life (HRQoL) among Korean older adults using a nationwide population-based survey.
Methods: Data from the 2021 Community Health Survey were used for this study.
The aim of this study is to investigate the potential of radiomic features extracted from postmortem computed tomography (PMCT) scans of the lateral cerebral ventricles (LCVs) to provide information on the time since death, or postmortem interval (PMI), a critical aspect of forensic medicine. Periodic PMCT scans, referred to as "sequential scans", were obtained from twelve corpses with known times of death, ranging from 5.5 to 273 h postmortem.
View Article and Find Full Text PDFRes Pract Thromb Haemost
November 2024
Department of Healthcare Surveillance and Bioethics, Section of Pharmacology, Catholic University School of Medicine, Rome, Italy.
Background: Serum thromboxane B (sTXB) is a validated biomarker of low-dose aspirin pharmacodynamics. In the original method, nonanticoagulated blood samples must be incubated at 37 °C immediately after withdrawal, centrifuged and serum supernatant should be frozen until assayed. Timely completion of all preanalytical steps may affect the feasibility and quality of sTXB measurements.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Section of Genomic Medicine, Department of Life Sciences and Public Health, Catholic University of Sacred Heart, 00168 Rome, Italy.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, responsible for Coronavirus Disease 2019 (COVID-19), exhibits a spectrum of clinical manifestations, ranging from asymptomatic to severe pulmonary dysfunction or death. The variability in COVID-19 severity has largely been attributed to the host's genetic characteristics, suggesting a polygenic genetic architecture, without significant strong evidence of sex-related genetic differences. In this Italian retrospective case-control study, we investigated the association between COVID-19 severity (severe vs.
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