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Disinfection of meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a remote non-thermal gas plasma. | LitMetric

Disinfection of meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a remote non-thermal gas plasma.

J Hosp Infect

UCD School of Chemical and Bioprocess Engineering, Centre for Synthesis and Chemical Biology, University College Dublin, Dublin, Ireland.

Published: July 2011

AI Article Synopsis

  • The study highlights the importance of disinfecting hospital surfaces to prevent infections, focusing on a new gas plasma system's effectiveness against biofilms.
  • Clinical strains of Staphylococcus epidermidis and MRSA were tested, showing that the disinfection process significantly reduced biofilm counts by 4 to 4.5 log₁₀ after just one hour, and even more with extended exposure.
  • The results indicate that the gas plasma system is effective not only on glass surfaces but also in medical device packaging, maintaining similar disinfection rates.

Article Abstract

The effective disinfection of hospital surfaces is recognised as an important factor in preventing hospital-acquired infections. The purpose of this study was to quantify the disinfection rate of a novel gas plasma system on clinically relevant biofilms. Clinical isolates of Staphylococcus epidermidis and meticillin-resistant Staphylococcus aureus (MRSA) were grown as biofilms on glass surfaces and tested in a disinfection container remote from the plasma source. The strains used in this study were known to produce substantial quantities of biofilm and average log₁₀ counts were 9.0 and 9.1 cfu/cm(2) for S. epidermidis and MRSA respectively. Counts were reduced by between 4 and 4.5 log₁₀ after 1h of exposure for MRSA and S. epidermidis respectively. More prolonged treatment in the case of MRSA biofilms resulted in a 5.5 log₁₀ reduction after 90 min. Biofilm samples were also placed in medical device packaging bags and similar rates of disinfection were observed.

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Source
http://dx.doi.org/10.1016/j.jhin.2011.03.019DOI Listing

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