A new series of glycine-derived ligands of the α(2)δ subunit of voltage gated calcium channels is described. Several novel compounds (7) based on (6) were prepared that possessed a potency <100 nM in the α(2)δ binding assay.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2011.04.045 | DOI Listing |
Publication Analysis
Top Keywords
n-alkylated glycines
4
glycines potent
4
potent α2δ
4
α2δ ligands
4
ligands series
4
series glycine-derived
4
glycine-derived ligands
4
ligands α2δ
4
α2δ subunit
4
subunit voltage
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!