AI Article Synopsis
- A stable palladium complex inspired by secondary phosphine oxide (SPO) allows for effective functionalization of C-H bonds.
- This process facilitates direct arylations and benzylations of (benz)oxazoles.
- Additionally, it introduces new methods for palladium-catalyzed C-H bond arylations on nonaromatic oxazolines.
Article Abstract
An air-stable, well-defined palladium complex derived from secondary phosphine oxide (SPO) (1-Ad)(2)P(O)H enabled efficient C-H bond functionalizations with ample scope, which set the stage for direct arylations and benzylations of (benz)oxazoles, as well as unprecedented palladium-catalyzed C-H bond arylations on nonaromatic oxazolines.
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| http://dx.doi.org/10.1021/ol200986x | DOI Listing |
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