The authors report on 3 cases of facial recurrent sclerosing basal cell carcinomas requiring large ablative cranio facial surgery and reconstruction involving regional or even free flaps. Special emphasis is made on the aggressive behavior of this specific histological form and on the necessity of an early diagnosis, a radical initial treatment and a close life time follow-up. Surgery with careful histological control of the margins is the treatment of choice whereas radiotherapy is an alternative for small lesions or nonsurgical patients. This early and aggressive therapeutic management is essential in order to avoid recurrences often requiring disfiguring surgery.
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http://dx.doi.org/10.3892/or.2.4.685 | DOI Listing |
Cureus
December 2024
Department of Radiology, Hospital Kuala Lumpur, Kuala Lumpur, MYS.
This retrospective case series evaluates the use of intralesional bleomycin injections in treating orbital venolymphatic malformations (OVLM). Three patients, a 7-year-old girl, a 37-year-old woman, and a 56-year-old man, presented with OVLM where the first two were recurrent cases with a history of failed sclerotherapy. All patients received multiple doses of intralesional bleomycin injections, resulting in significant reductions in lesion size, decreased proptosis, and pain relief.
View Article and Find Full Text PDFEuroasian J Hepatogastroenterol
December 2024
Department of Radiation Oncology, Institute of Liver and Biliary Sciences, New Delhi, India.
Background: The purpose of the present study was to evaluate clinicopathological characteristics, patterns of recurrence, survival outcomes, and implications for the addition of chemoradiotherapy for patients with resected perihilar and intrahepatic cholangiocarcinoma (CCA).
Materials And Methods: For the present retrospective study, we identified 38 and 10 patients with resected perihilar and intrahepatic CCA. In perihilar CCA, adjuvant treatment was given as chemotherapy ( = 13) or chemoradiotherapy ( = 10).
Cancers (Basel)
December 2024
Department of Pathology, Turku University Hospital, 20520 Turku, Finland.
(1) Low-grade adenosquamous carcinoma (LGASC) is a rare subtype of metaplastic breast carcinoma (MpBC), accounting for fewer than 0.05% of breast cancer cases. Unlike the typically aggressive nature of MpBCs, LGASC is an indolent tumor with an excellent prognosis.
View Article and Find Full Text PDFCureus
December 2024
Department of Ophthalmology, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, SAU.
Int Cancer Conf J
January 2025
Department of Allergy and Respiratory Medicine, Okayama University Hospital, Okayama, Japan.
Pulmonary sclerosing pneumocytoma (PSP) is a rare form of lung cancer that occasionally presents with lymph node and extrapulmonary metastases, and multiple lesions. The treatment of metastatic PSP remains undefined. This study reports the case of a 48-year-old female patient diagnosed with PSP following surgical intervention for a solitary nodule in the left lower lobe.
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