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Novel Variant of New Delhi Metallo-Beta-Lactamase () Discovered in a Clinical Strain of from the United Arab Emirates: An Emerging Challenge in Antimicrobial Resistance.
Antibiotics (Basel)
December 2024
Tawam Hospital, Al Ain P.O. Box 5674, United Arab Emirates.
Carbapenem resistance poses a significant health threat. This study reports the first detection and characterization of a novel variant of New Delhi metallo-β-lactamase () in from the United Arab Emirates (UAE), including its genetic context and relationship to global strains. NDM-60-producing was isolated from a rectal swab during routine screening.
View Article and Find Full Text PDFImport of global high-risk clones is the primary driver of carbapenemase-producing in Norway.
J Med Microbiol
January 2025
Norwegian Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Troms, Norway.
Infections by carbapenemase-producing (CP-Pa) are concerning due to limited treatment options. The emergence of multidrug-resistant (MDR) high-risk clones is an essential driver in the global rise of CP-Pa. Insights into the molecular epidemiology of CP-Pa are crucial to understanding its clinical and public health impact.
View Article and Find Full Text PDFInsights into the different mechanisms of Autophagy and Apoptosis mediated by Morbilliviruses.
Virology
December 2024
Department of Microbiology, University of Delhi South Campus, New Delhi, 110021, India. Electronic address:
Article Synopsis
- Viruses, like morbilliviruses, are parasites that depend on host cells and have evolved to manipulate the immune system by altering host proteins involved in biological processes.
- Morbilliviruses can interfere with programmed cell death mechanisms, such as autophagy and apoptosis, either using autophagosomes to delay host defenses or triggering apoptosis to spread infection.
- Recent research on the interaction between these pathways opens up possibilities for using morbilliviruses in developing new therapeutic strategies.
Digital supportive supervision (DiSS) of maternal health, child health and nutrition (MCHN) service delivery in Rajasthan, India: study protocol for impact evaluation and cost-effectiveness analysis.
BMJ Open
December 2024
Department of Community Medicine and School of Public Health, Post Graduate Institute of Medical Education and Research, Chandigarh, India
Background: A digital supportive supervision (DiSS) tool was developed and implemented in Rajasthan, India, to enhance the coverage and quality of maternal health, child health and nutrition (MCHN) services. This study aims to assess the impact and cost-effectiveness of DiSS compared to traditional paper-based supportive supervision.
Methods And Analysis: A quasi-experimental research design incorporating interrupted time series regression analysis will be employed to evaluate the impact of DiSS.
School-based adolescent health survey in Himachal Pradesh, India: study design and protocol.
Front Public Health
December 2024
Mamta Health Institute for Mother and Child (HIMC), New Delhi, India.
Background: The World Health Organization defined adolescent age group as a life span between 10 and 19 years. Adolescence is a phase of transition from childhood to adulthood, it is a unique stage for human development and a very sensitive period for laying the foundation of good health. Investment in this life-stage yields triple dividend.
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