The ankle-brachial index (ABI) is a method used widely for peripheral arterial disease (PAD) diagnosis and cardiovascular risk prediction. This study validated automated ABI measurements taken using an oscillometric blood pressure (BP) monitor allowing simultaneous arm-leg BP measurements. A total of 93 patients (hypertension 83%; dyslipidemia 72%; diabetes 45%; cardiovascular disease 23%; smoking 15%) were submitted to Doppler and automated ABI measurements, performed using a professional oscillometric BP monitor (Microlife WatchBP Office; triplicate simultaneous arm-leg BP measurements), in a randomized order. The mean difference between the Doppler reading (1.08 ± 0.17) and (1) the first oscillometric ABI reading was 0.03 ± 0.11, (2) the average of two oscillometric readings was 0.02 ± 0.10 and (3) the average of three oscillometric readings was 0.02 ± 0.09 (P < 0.01 for all). Strong correlations were found between oscillometric and Doppler ABI (r 0.80, 0.85 and 0.86 for single and average of two and three oscillometric readings, respectively; P < 0.001 for all). Agreement between oscillometric and Doppler ABI in diagnosing PAD (Doppler ABI < 0.9) was found in 95% of cases (κ 0.79; agreement in diabetics: 94%, κ 0.79). A receiver operating characteristic (ROC) curve revealed area under the curve at 0.98, with a 0.97 oscillometric ABI cutoff for optimal sensitivity (92%) and specificity (92%) in diagnosing PAD. Average time for automated ABI measurement was 5.8 vs. 9.3 min for Doppler (P < 0.001). Doppler and oscillometric ABI were associated and predicted (multivariate regression analysis) by the same cardiovascular risk factors (pulse pressure, smoking and cardiovascular disease history). Automated ABI measurement using a professional BP monitor allowing simultaneous arm-leg BP measurements appears to be a reliable and faster alternative to Doppler measurement.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/hr.2011.53 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Neurological Pupil Index and Intracranial Hypertension in Patients With Acute Brain Injury: A Secondary Analysis of the ORANGE Study.
JAMA Neurol
December 2024
School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Importance: Invasive intracranial pressure (ICP) is the standard of care in patients with acute brain injury (ABI) with impaired consciousness. The Neurological Pupil Index (NPi) obtained by automated pupillometry is promising for noninvasively estimating ICP.
Objectives: To evaluate the association between repeated NPi and invasive ICP values.
Enhancing sugarcane leaf disease classification through a novel hybrid shifted-vision transformer approach: technical insights and methodological advancements.
Environ Monit Assess
December 2024
Department of Chemistry, Easwari Engineering College, Chennai, Tamil Nadu, India.
Article Synopsis
- Sugarcane farming is highly organized in India, the second-largest producer, but is heavily impacted by diseases affecting crop yields.
- A new Hybrid Shifted-Vision Transformer model combines Vision Transformer architecture with advanced techniques to enhance the classification of sugarcane leaf diseases, capturing essential features at various scales.
- The model uses self-supervised learning and data augmentation to improve performance and address class imbalances, achieving a high accuracy of 98.5% in disease detection, which is vital for effective agricultural management.
Compact Arterial Monitoring Device Use in Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): A Simple Validation Study in Swine.
Cureus
October 2024
Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, USA.
Article Synopsis
- - Hemorrhage is the main cause of preventable death in trauma situations, leading to military and civilian advancements in medical practices, particularly through the use of tourniquets to manage extremity bleeding and save lives.
- - While tourniquets have significantly decreased deaths from bleeding in military settings, noncompressible hemorrhage still poses a major risk, especially before patients receive definitive medical care.
- - The study explores using a small, disposable pressure monitor during resuscitative endovascular balloon occlusion of the aorta (REBOA) to enhance blood pressure monitoring, facilitate better resuscitation practices, and reduce the need for blood products in extreme environments.
A rapid, sensitive, and high-throughput pathogen detection method and application of identifying pathogens based on multiplex PCR technology combined with capillary electrophoresis.
Diagn Microbiol Infect Dis
January 2025
Department of Neurosurgery, Zhongnan hospital of Wuhan university, China. Electronic address:
Respiratory infections are one of the leading causes of death worldwide. Rapid and accurate detection of pathogens is crucial for timely treatment. This study established a detection method based on multiplex PCR combined with capillary electrophoresis, capable of simultaneously detecting 28 common respiratory pathogens.
View Article and Find Full Text PDFAn automated commercial open access assay for detection of Mycoplasma genitalium macrolide resistance.
APMIS
January 2025
Clinical Microbiology, Infection Prevention and Control, Office for Medical Services, Lund, Sweden.
Article Synopsis
- Azithromycin is the main antibiotic used to treat Mycoplasma genitalium (MG), but resistance due to mutations is becoming a concern, particularly in the 23S rRNA gene.
- A study evaluated the Panther Fusion analyzer for detecting macrolide resistance mutations (MRM) and wild type (WT) MG in clinical samples, finding a 91% agreement with an established PCR method.
- The Panther Fusion detected MRM in 20% and WT in 62% of samples, showing potential for easier testing but slightly lower effectiveness for macrolide susceptibility testing, suggesting the need for additional testing methods when results are unclear.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!