AI Article Synopsis
- THC is a key part of marijuana that can help kill cancer cells by a process called autophagy.
- Scientists discovered that a protein called midkine can change how THC works, making it less effective against glioma cells (a type of brain cancer).
- This research helps us understand how different signals in the body can affect how THC does its job against cancer.
Article Abstract
Δ⁹-tetrahydrocannabinol (THC), the main active component of marijuana, promotes cancer cell death via autophagy stimulation. We find that activation of the tyrosine kinase receptor ALK by its ligand midkine interferes with the signaling mechanism by which THC promotes autophagy-mediated glioma cell death.
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| http://dx.doi.org/10.4161/auto.7.9.15866 | DOI Listing |
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