p-hydroxyacetophenone amides from Cystobacter ferrugineus, strain Cb G35.

J Nat Prod

Research Group Microbial Drugs, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.

Published: June 2011

AI Article Synopsis

  • A new family of six novel compounds called p-hydroxyacetophenone amides was discovered from the bacterium Cystobacter ferrugineus strain Cb G35.
  • The structures of these compounds were determined using advanced techniques like ESI-TOF mass spectrometry and NMR spectroscopy.
  • Experiments using labeled precursors [¹³C₉,¹⁵N]-tyrosine and [d₁₀]-leucine helped identify the building blocks used to produce one of the compounds.

Article Abstract

A family of six novel p-hydroxyacetophenone amides, 1-6, was isolated from Cystobacter ferrugineus, strain Cb G35. Their structures were elucidated by ESI-TOF mass spectrometry and NMR spectroscopy. Feeding experiments with labeled [¹³C₉,¹⁵N]-tyrosine and [d₁₀]-leucine identified the biosynthetic precursors of 1.

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http://dx.doi.org/10.1021/np1006789DOI Listing

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Article Synopsis
  • A new family of six novel compounds called p-hydroxyacetophenone amides was discovered from the bacterium Cystobacter ferrugineus strain Cb G35.
  • The structures of these compounds were determined using advanced techniques like ESI-TOF mass spectrometry and NMR spectroscopy.
  • Experiments using labeled precursors [¹³C₉,¹⁵N]-tyrosine and [d₁₀]-leucine helped identify the building blocks used to produce one of the compounds.
View Article and Find Full Text PDF

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