In the title compound, C(14)H(15)BrN(2)O(3), the dihydro-pyrimidin-one ring adopts a boat conformation. In the crystal, adjacent mol-ecules are linked through N-H⋯O hydrogen bonds forming an R(2) (2)(8) ring motif and generating a zigzag chain extending in [010].
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011541 | PMC |
| http://dx.doi.org/10.1107/S1600536810049019 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Self-Assembly and Drug Encapsulation Properties of Biocompatible Amphiphilic Diblock Copolymers.
Langmuir
January 2025
Department of Applied Chemistry, Graduate School of Engineering, University of Hyogo, Shosha, Himeji, Hyogo 671-2201, Japan.
To prepare amphiphilic diblock copolymers (MP), a controlled radical polymerization approach was employed, incorporating hydrophilic poly(2-(methacryloyloxy)ethyl phosphorylcholine) (PMPC) with hydrophobic poly(3-methoxypropyl acrylate) (PMPA). The synthesized diblock copolymers feature a PMPC block with a degree of polymerization (DP) of 100 and a PMPA block with DP (=) values of 171 and 552. The hydrophilic PMPC block exhibits biocompatibility, such as inhibition of platelet and protein adsorption, because of its hydrophilic pendant zwitterionic phosphorylcholine groups that have the same chemical structure as cell membrane surfaces.
View Article and Find Full Text PDFMetal-organic frameworks for the separation of xylene isomers.
Chem Soc Rev
January 2025
Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of New Power Batteries, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
Xylene isomers, including -xylene (X), -xylene (X), -xylene (X), and ethyl benzene (EB), are important raw materials in industry. The separation of xylene isomers has been recognized as one of the "seven chemical separations to change the world". However, because of their similar physicochemical properties, totally separating four xylene isomers has remained a big challenge until now.
View Article and Find Full Text PDFC-H Activation and Sequential Addition to Dienes and Imines: Synthesis of Amines with -Quaternary Centers and Mechanistic Studies on the Complex Interplay Between the Catalyst and Three Reactants.
ACS Catal
December 2024
Department of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
A Rh(III)-catalyzed sequential C-H bond addition to dienes and in situ formed aldimines was developed, allowing for the preparation of otherwise challenging to access amines with quaternary centers at the -position. A broad range of dienes were effective inputs and installed a variety of aryl and alkyl substituents at the quaternary carbon site. Aryl and alkyl sulfonamide and carbamate nitrogen substituents were incorporated by using different formaldimine precursors.
View Article and Find Full Text PDFPharmacological Profiling of and : Unraveling the Antibacterial and Anti-Cancer Potential of Chemically Active Metabolites.
J Cancer
January 2025
Department of Basic Dental Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University (PNU), P.O. Box 84428, Riyadh 11671, Saudi Arabia.
The increasing prevalence of cancer and bacterial resistance necessitates more effective anti-cancer and anti-bacterial treatments. This study explores the potential of medicinal plants, specifically () and (), in addressing this need, aiming to uncover new therapeutic interventions. Various extraction methods for the leaves of and were employed to investigate the anti-bacterial and anti-cancer properties of these herbs.
View Article and Find Full Text PDFPimenov: A potent antifungal medicinal plant.
Curr Med Mycol
May 2024
Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Background And Purpose: species are well-known antifungal medicinal plants. (Apiaceae family) is a rarely investigated plant endemic to Iran. The present study aimed to assess the antifungal, antibacterial, antioxidant, and cytotoxic activities of root extracts of different plants.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!