In the title compound, C(13)H(22)N(4)O(2)S(2), the six-membered ring displays a half-chair conformation. The olefin amine unit is close to being coplanar with the imidazolidine ring (r.m.s. deviation = 0.059 Å). The dithiol-ane ring adopts a twisted conformation. In the crystal, mol-ecules are linked by weak C-H⋯O inter-actions.
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http://dx.doi.org/10.1107/S1600536810033829 | DOI Listing |
Stem Cell Res Ther
December 2024
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, People's Republic of China.
Background: Mesenchymal stem cells (MSCs) are widely applied in the treatment of various clinical diseases and in the field of medical aesthetics. However, MSCs exhibit greater heterogeneity limited stability, and more complex molecular and mechanistic characteristics compared to conventional drugs, making rapid and precise monitoring more challenging.
Methods: Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive, tractable and low-cost fingerprinting technique capable of identifying a wide range of molecules related to biological processes.
Cancer Imaging
December 2024
Division of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Background: To verify overall survival predictions made with residual convolutional neural network-determined morphological response (ResNet-MR) in patients with unresectable synchronous liver-only metastatic colorectal cancer (mCRC) treated with bevacizumab-based chemotherapy (BBC).
Methods: A retrospective review of liver-only mCRC patients treated with BBC from December 2011 to Apr 2021 was performed. Patients who had metachronous liver metastases or received locoregional treatment before the initiation of BBC were excluded.
Inorg Chem
December 2024
College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan, P. R. China.
Inspired by the rapid growth of Ru-based complexes as molecular ammonia oxidation catalysts, we propose novel Ru-dpp complexes bearing a nitrogen donor as the axial ligand into the ammonia oxidation catalysts family. Herein, a series of Ru-dpp complexes [Ru(-,',″-dpp)(bpy)(L)]·PF (where Hdpp = 2-[5-(pyridin-2-yl)-1-pyrrol-2-yl]pyridine; bpy = 2,2'-bipyridine; L = pyridine (); 4-methylpyridine (); pyrimidine (); isoquinoline ()) containing aromatic nitrogen donor axial ligand are synthesized and fully characterized by NMR, IR, and ESI-MS. The structural analysis displays that dpp as a pincer ligand coordinates to ruthenium, and nitrogen donor L binds to ruthenium at an axial ligand.
View Article and Find Full Text PDFStem Cell Res Ther
November 2024
Institute of Biophysics, HUN-REN Biological Research Centre, Szeged, 6726, Hungary.
Background: One of the most severe consequences of ageing is cognitive decline, which is associated with dysfunction of the brain microvasculature. Thus, repairing the brain vasculature could result in healthier brain function.
Methods: To better understand the potential beneficial effect of endothelial progenitor cells (EPCs) in vascular repair, we studied the adhesion and integration of EPCs using the early embryonic mouse aorta-gonad-mesonephros - MAgEC 10.
Spectrochim Acta A Mol Biomol Spectrosc
February 2025
Department of Chemistry, Dr. Bhimrao Ambedkar University, Agra 282002, U.P, India. Electronic address:
The titled molecule 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (ANMC) is a core of anticancer drug dasatinib (leukemia). Its derivatives exhibited bioactivity against breast cancer. Experimentally, the titled compound was described using NMR (H NMR and C NMR), FTIR and UV-visible spectroscopy.
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