The asymmetric unit cell of the title compound, C(18)H(18)N(2)O, contains four molecules. In the crystal structure, an inter-molecular N-H⋯N hydrogen bond helps to establish the packing.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006893PMC
http://dx.doi.org/10.1107/S1600536810022130DOI Listing

Publication Analysis

Top Keywords

r-4-phenyl-2-[s-1234-tetra-hydro-isoquinolin-3-yl]-45-dihydro-13-oxazole asymmetric
4
asymmetric unit
4
unit cell
4
cell title
4
title compound
4
compound c18h18n2o
4
c18h18n2o molecules
4
molecules crystal
4
crystal structure
4
structure inter-molecular
4

Similar Publications

The NAD(P)H-dependent carbonyl reductase from Candida parapsilosis ATCC 7330 catalyses the asymmetric reduction of ethyl 4-phenyl-2-oxobutanoate to ethyl (R)-4-phenyl-2-hydroxybutanoate, a precursor of angiotensin-converting enzyme inhibitors such as Cilazapril and Benazepril. The carbonyl reductase was expressed in Escherichia coli and purified by GST-affinity and size-exclusion chromatography. Crystals were obtained by the hanging-drop vapour-diffusion method and diffracted to 1.

View Article and Find Full Text PDF

The asymmetric unit cell of the title compound, C(18)H(18)N(2)O, contains four molecules. In the crystal structure, an inter-molecular N-H⋯N hydrogen bond helps to establish the packing.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!