The asymmetric unit cell of the title compound, C(18)H(18)N(2)O, contains four molecules. In the crystal structure, an inter-molecular N-H⋯N hydrogen bond helps to establish the packing.
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http://dx.doi.org/10.1107/S1600536810022130 | DOI Listing |
Acta Crystallogr Sect F Struct Biol Cryst Commun
March 2013
Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600 036, India.
The NAD(P)H-dependent carbonyl reductase from Candida parapsilosis ATCC 7330 catalyses the asymmetric reduction of ethyl 4-phenyl-2-oxobutanoate to ethyl (R)-4-phenyl-2-hydroxybutanoate, a precursor of angiotensin-converting enzyme inhibitors such as Cilazapril and Benazepril. The carbonyl reductase was expressed in Escherichia coli and purified by GST-affinity and size-exclusion chromatography. Crystals were obtained by the hanging-drop vapour-diffusion method and diffracted to 1.
View Article and Find Full Text PDFActa Crystallogr Sect E Struct Rep Online
June 2010
The asymmetric unit cell of the title compound, C(18)H(18)N(2)O, contains four molecules. In the crystal structure, an inter-molecular N-H⋯N hydrogen bond helps to establish the packing.
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