Combined clinical, psychologic and neurophysiological investigation was conducted in children with slow-progredient schizophrenia: with dominant affective disorders and hypomaniac states (Group I, 14 patients), and with predominant neurosis-like and psychopathy-like pathology (Group II, 12 patients). The patients distinctly differed in not only the clinical course of the disease but also according to neuropsychological investigations of memory, pathopsychological and EEG studies. These data are reliably intercorrelated. A high incidence of visual mnestic, marked perception disorders, and frequent focal signs of lesion of parieto-occipital cortex with cortical irritation were all characteristics of the Group I. In Group II a high inhibitability of the traces characteristic of the diencephalic-brainstem dysfunction, predominant impairment of objective-substantional thinking and the symptoms of brainstem irritation were marked.
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