Desmoid tumor, also known as aggressive or deep fibromatosis or musculoaponeurotic fibromatosis, is a rare tumor. Desmoids are characterized by their ability to locally infiltrate; while frequently locally recurrent, they lack metastatic potential. Desmoids typically arise within the abdomen or abdominal wall, but can be extra-abdominal, most commonly in the proximal extremities. The infiltrative and recurrent nature of desmoid tumors can render surgical resection challenging if acceptable function and cosmesis is to be maintained. Consequently, desmoid management frequently involves a multidisciplinary approach that combines the expertise of several surgical specialists, for example, surgical oncologists and plastic surgeons, and also medical and radiation oncologists. As will be reviewed in this article, working together before undertaking any definitive therapies, such expert teams may be optimally positioned to offer patients superior functional and aesthetic outcomes based on maximizing therapeutic efficacy while minimizing treatment-related morbidities.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/SAP.0b013e3182084cf6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A case of a patient with erythema annulare centrifugum found to have aggressive fibromatosis.
JAAD Case Rep
January 2025
Department of Dermatology, University of California San Francisco, San Francisco, California.
Enhancing rare cancer care in developing countries through patient advocacy: insights from the Desmoid Tumor Brazilian Association.
Ther Adv Med Oncol
January 2025
Department of Medical Oncology, Sarcoma and Bone Tumors Reference Center, A.C. Camargo Cancer Center, R. Prof. Antônio Prudente, 211, São Paulo, SP 01509-010, Brazil.
Introduction: Desmoid tumors are soft-tissue neoplasms that can have profound impacts on the lives of people living with such diseases. As they are rare tumors, patients often have difficulty finding teams specialized in sarcomas and support networks. In low- and middle-income countries, the challenges are exacerbated due to a need for established networks and medication access.
View Article and Find Full Text PDFRisk factors and protective measures for desmoid tumours in familial adenomatous polyposis: retrospective cohort study.
BJS Open
December 2024
Unit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumouri, Milan, Italy.
Background: Familial adenomatous polyposis is a cancer-predisposing syndrome caused by germline pathogenic variants of the adenomatous polyposis coli gene, leading to numerous colorectal polyps and a high risk of colorectal cancer. Desmoid tumours have become significant in the management of familial adenomatous polyposis after a colectomy, yet the exact incidence remains undetermined due to a lack of dedicated surveillance.
Methods: This retrospective study accessed data from the prospectively maintained Hereditary Digestive Tumours Registry from 2000 to 2023.
Desmoid fibromatosis post-cervical spine surgical intervention.
BJR Case Rep
January 2025
Dubai Health, Dubai 1853, United Arab Emirates.
Article Synopsis
- Desmoid tumours are rare benign growths that can aggressively invade surrounding tissues, especially near nerves and blood vessels, making them difficult to treat.
- Their exact cause is unknown, but they are more common in females and may be linked to factors like trauma, surgery, or inflammation, suggesting possible genetic or hormonal influences.
- A case study highlights a 34-year-old woman who developed a desmoid tumour in her neck after neck surgery; despite surgical removal, the tumour recurred, necessitating a second operation for complete treatment.
Familial adenomatous polyposis family with clustering of psychiatric disorders.
Jpn J Clin Oncol
January 2025
Department of Clinical Oncology, Graduate School of Medicine, Akita University, Hondo 1-1-1, Akita, 010-8543, Japan.
Article Synopsis
- Familial adenomatous polyposis (FAP) is an inherited disorder caused by mutations in the APC gene, leading to colorectal polyps and other health issues.
- This condition can also cause extracolonic manifestations like desmoid tumors and various mental disorders in affected families.
- A case study highlights the importance of mental health care in genetic counseling, as a family with FAP showed connections between the disorder and mental health issues, including autism spectrum disorder and intellectual disabilities.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!