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Tumor Intrinsic Immunogenicity Suppressor SETDB1 Worsens the Prognosis of Patients with Hepatocellular Carcinoma.
Cells
December 2024
College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Hepatocellular carcinoma (HCC) is clinically distinguished by its covert onset, rapid progression, high recurrence rate, and poor prognosis. Studies have revealed that SETDB1 (SET Domain Bifurcated 1) is a histone H3 methyltransferase located on chromosome 1 and plays a crucial role in carcinogenesis. Therefore, we aimed to evaluate the clinical significance of SETDB1 expression in HCC.
View Article and Find Full Text PDFIdentification of immune characteristics of two lung adenocarcinoma subtypes based on immune- and pyroptosis-related genes to improve immunotherapy.
Bull Cancer
January 2025
Department of Respiratory and Critical Care Medicine, Baoji High-Tech Hospital, Baoji, 721000 Shaanxi, China. Electronic address:
Background: Lung adenocarcinoma (LUAD) is the most prevalent histological subtype of lung cancer. Pyroptosis is a programmatic cell death linked to inflammation.
Methods: The data information of 541 LUAD samples and 59 normal samples were obtained from TCGA database.
Ultra-Processed Foods and Childhood Obesity: Current evidence and perspectives.
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January 2025
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Str., 11527, Athens, Greece.
Purpose Of The Review: Ultra-processed foods (UPFs) represent foods that have undergone substantial industrial processing, such as the addition of preservatives and various other ingredients, thereby making them more tasty, appealing and easy to consume. UPFs are often rich in sugars, saturated fats and salt, while they are low in essential nutrients.The aim of this review is to examine the relationship between the widespread consumption of UPFs and the development of obesity among children and adolescents.
View Article and Find Full Text PDFAccelerated stochastic processes of plankton community assembly due to tidal restriction by seawall construction in the Yangtze River Estuary.
Mar Environ Res
December 2024
School of Life Sciences, East China Normal University, Shanghai, China; Yangtze Delta Estuarine Wetland Ecosystem Observation and Research Station, Ministry of Education and Shanghai Science and Technology Committee, Shanghai, China. Electronic address:
Seawall construction has complex ecological impacts. However, the ecological mechanisms within plankton communities under tidal restriction resulting from seawall construction remain unexplored. Using environmental DNA (eDNA) metabarcoding, this study examined the impact of seawall construction on the assembly process of planktonic eukaryote and bacteria communities from the unrestricted area and the tide-restricted area in the Chongming Dongtan Nature Reserve of Yangtze River Estuary.
View Article and Find Full Text PDFRegulation of desiccation-immersion cycle on the rate and fate of dissolved organic carbon release by Ulva pertusa.
Mar Environ Res
December 2024
Key Laboratory of Coastal Biology and Biological Resource Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China; University of Chinese Academy of Sciences, Beijing 100049, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China. Electronic address:
Macroalgae widely distribute in intertidal zones, one of blue carbon organisms. However, the regulatory mechanisms of tide on the carbon sequestration of macroalgae are still unclear. This study explored the effects of desiccation-rewetting cycles induced by tide on dissolved organic carbon (DOC) release from Ulva pertusa, which is prevalent from high to low tidal zones.
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