AI Article Synopsis

  • Acromegaly is a serious disease that leads to higher health issues and lower life expectancy, often diagnosed late due to its subtle symptoms and lack of recognition.
  • Early diagnosis and effective treatment are crucial to reduce health complications and normalize death rates associated with the disease.
  • The Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism aims to outline key clinical signs for suspicion of acromegaly, diagnosis methods, and recommended treatment approaches at specialized centers.

Article Abstract

Acromegaly is a disease associated with increased morbidity and reduced life expectancy. Because of its insidious character and its non-recognition, the diagnosis is often made with delay, which, along with the complications related to GH/IGF-I excess, determines high morbidity and mortality. However, an early diagnosis and an effective treatment reduce the morbidity and normalize the mortality rate. In this publication, the goal of Neuroendocrinology Department from Brazilian Society of Endocrinology and Metabolism is to disclose which clinical set should arouse the suspicious of acromegaly and how to diagnose it. Furthermore, we discuss the most effective and safe approach to perform the treatment of acromegaly, emphasizing that it must be carried out in reference centers. Therefore, based on data published in journals with recognized scientific level and authors' experience, recommendations are presented for diagnosis and treatment of the disease.

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http://dx.doi.org/10.1590/S0004-27302011000200001DOI Listing

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