(4S,5S)-2-(4-Chloro-phen-yl)-1,3-dioxolane-4,5-dicarboxamide.

Acta Crystallogr Sect E Struct Rep Online

School of Pharmaceutical Sciences, Nanjing University of Technology, Xinmofan Road No.5 Nanjing, Nanjing 210009, People's Republic of China.

Published: July 2009

The title compound, C(11)H(11)ClN(2)O(4), is an important inter-mediate for the preparation of platinum anti-cancer drugs. The dioxolane ring adopts a twist conformation with an equatorially attached chloro-phenyl substituent. In the crystal structure, mol-ecules are linked into a two-dimensional network parallel to (001) by N-H⋯O and C-H⋯O hydrogen bonds.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977328PMC
http://dx.doi.org/10.1107/S1600536809027494DOI Listing

Publication Analysis

Top Keywords

4s5s-2-4-chloro-phen-yl-13-dioxolane-45-dicarboxamide title
4
title compound
4
compound c11h11cln2o4
4
c11h11cln2o4 inter-mediate
4
inter-mediate preparation
4
preparation platinum
4
platinum anti-cancer
4
anti-cancer drugs
4
drugs dioxolane
4
dioxolane ring
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!