Abacavir methanol 2.5-solvate.

Acta Crystallogr Sect E Struct Rep Online

Department of Chemistry, Penn State Worthington Scranton, 120 Ridge View Drive, Dunmore, Pennsylvania 18512, USA.

Published: July 2009

THE STRUCTURE OF ABACAVIR (SYSTEMATIC NAME: {(1S,4R)-4-[2-amino-6-(cyclo-propyl-amino)-9H-purin-9-yl]cyclo-pent-2-en-1-yl}methanol), C(14)H(18)N(6)O·2.5CH(3)OH, consists of hydrogen-bonded ribbons which are further held together by additional hydrogen bonds involving the hydroxyl group and two N atoms on an adjacent purine. The asymmetric unit also contains 2.5 mol-ecules of methanol solvate which were grossly disordered and were excluded using SQUEEZE subroutine in PLATON [Spek, (2009 ▶). Acta Cryst. D65, 148-155].

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977439PMC
http://dx.doi.org/10.1107/S1600536809027743DOI Listing

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